HUPO Connect 2020 Program

Important Notice: Sessions 1B through 9B are repeated sessions to accommodate all timezones. Please note that the program is subject to change without notice. All sessions are listed in UTC time (Coordinated Universal Time). Please view the World Clock Converter for your timezone.

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  • October 19, 2020


  • October 20, 2020


  • October 21, 2020


  • October 22, 2020


  • Opening Remarks, Stephen Pennington, Ireland
    Introduction to the HUPO Connect 2020 Platform and Programme, Michelle Hill, Australia
    Celebrating the High-Stringency Human Proteome Blueprint, Gil Omenn, United States
    Human Proteome Resources Panel, Gil Omenn, United States, Ed Nice, Australia, Lydie Lane, Switzerland,
    Eric Deutsch, United States, Cecilia Lindskog-Bergstrom, Sweden, Ulrike Kusebauch, United States, Young Ki, Korea
    Global Proteomic Exploration of COVID-19: Infection and Therapeutics, Stephen Pennington, Ireland, Yu-Ju Chen, Taiwan

  • Chair: Rudolf Aebersold, Switzerland
    Co-Chair: Viviana Greco, Italy
    Beyond the Genome: Facilitating Precision Medicine with Targeted Proteomic Assays, Amanda Paulovich, United States
    Development of Saliva Protein Biomarkers to Detect and Monitor Oral Cancer, Jau-Song Yu, Taiwan
    Discovery of Precision Medicines and Chemical Probes for Cancer: Role of Proteomics and Genomics, Paul Workman, United Kingdom

  • Chair: Yu Ju Chen, Taiwan
    Co-Chair: Melanie White, Australia
    Proximity interactomes for SARS CoV-2: toward a neighbourhood view of infection, Anne-Claude Gingras, Canada
    Development and usage of high-performing diagnostic test of SARS-CoV-2 antibodies, Sophia Hober, Sweden
    Using Mass Spectrometry to Reduce the Harm Caused by the SARS-Cov2 Virus, and How Sebum Is a Unique Biofluid With Great Diagnostic Potential, Perdita Barran, United Kingdom

    This session is supported by:
    Click Here to Watch Video

  • Chair: HoJeong Kwon, Korea
    Co-Chair: Scott Bringans, Australia
    Biology, Pathogenesis, and Treatment of Viral Infections Viewed Through the Lens of Proteomics, Ileana Cristea, United States
    Harnessing Glycomics and Glycoproteomics for Cardiovascular Precision Medicine, Rebekah Gundrey, United States
    The wondrous world of molecules in context: Image-and-omics at the single cell level, Ron Heeren, The Netherlands

  • Chairs: Rob Rivers, United States, Alexander Hogrebe, United States
    A Mentor's Perspective: Lisa Jones, United States
    A Mentee's Perspective: Brandon T. Ruotolo, United States

  • Explore the Proteome Using CETSA MS, Tomas Friman

    This industry seminar is supported by:
    For more details on the virtual Industry Seminars, please visit the Confirmed Sponsors & Virtual Seminars page.

  • TMT-Based Comparative Interactomics of SARS-CoV-2 and Coronavirus Non-Structural Protein Homologs to Identify Shared and Unique Host-Cell Dependencies, Lars Plate
    Providing COVID-19 Clarity Using TMT Reagents for Precision Measurements, Ryan Bomgarden

    This industry seminar is supported by:
    For more details on the virtual Industry Seminars, please visit the Confirmed Sponsors & Virtual Seminars page.

  • Chair: Michael Snyder, United States
    Co-Chair: Danni Li, United States
    Beyond the Genome: Facilitating Precision Medicine with Targeted Proteomic Assays, Amanda Paulovich, United States
    Development of Saliva Protein Biomarkers to Detect and Monitor Oral Cancer, Jau-Song Yu, Taiwan
    Discovery of Precision Medicines and Chemical Probes for Cancer: Role of Proteomics and Genomics, Paul Workman, United Kingdom

  • Chair: Subhra Chakraborty, India
    Co-Chair: Harry Whitwell, United Kingdom
    Proximity interactomes for SARS CoV-2: toward a neighbourhood view of infection, Anne-Claude Gingras, Canada
    Development and usage of high-performing diagnostic test of SARS-CoV-2 antibodies, Sophia Hober, Sweden
    Using Mass Spectrometry to Reduce the Harm Caused by the SARS-Cov2 Virus, and How Sebum Is a Unique Biofluid With Great Diagnostic Potential, Perdita Barran, United Kingdom

    This session is supported by:
    Click Here to Watch Video

  • Chair: Jennifer Van Eyk, United States
    Co-Chair: Aleksandra Nita-Lazar, United States
    Biology, Pathogenesis, and Treatment of Viral Infections Viewed Through the Lens of Proteomics, Ileana Cristea, United States
    Harnessing Glycomics and Glycoproteomics for Cardiovascular Precision Medicine, Rebekah Gundrey, United States
    The wondrous world of molecules in context: Image-and-omics at the single cell level, Ron Heeren, The Netherlands

  • Chair: Cecilia Lindskog, Sweden
    Co-Chair: Deborah Penque, Portugal
    ATLANTiC: Proteome Activity Landscapes of Tumor Cell Lines Determine Drug Responses, Bernhard Kuster, Germany
    Deep Visual Proteomics for Systems Biology, Matthias Mann, Germany
    Regulation of Hypoxia-inducible Factors by Oxygen-dependent Degradation, Gregg Semenza, United States

    This session is supported by:

  • Chair: Michelle Hill, Australia
    Co-Chair: Nicolai Bache, Denmark
    Development of a Pan-coronavirus Proteome Serological Assay, Josh LaBaer, United States
    The 3D Proteome and the Potential for Conformational Biomarkers, John Yates, United States
    Protein Biomarker Quantification by LCMS Enabling Gene Therapy and Biotherapeutics Development in Biopharma, Hendrik Neubert, United States

    This session is supported by:

  • Chair: Paola Roncada, Italy
    Co-Chair: Fábio CS Nogueira, Brazil
    In-cell Protein Footprinting: A Tool for Structural Biology Across the Proteome, Lisa Jones, United States
    Single-cell Proteomic and Transcriptomic Analysis of Macrophage Heterogeneity, Nikolai Slovov, United States
    Mass Spectrometry Proteomics for Single-cell Neuroscience, Peter Nemes, United States

    This session is supported by:

  • Live Annual General Meeting and Kahoot Quiz

  • Chair: Giuseppe Palmisano, Brazil
    Finalists:
    Precision Mapping of O Linked N Acetylglucosamine Sites in Proteins Using Ultraviolet Photodissociation Mass Spectrometry, Edwin Escobar, United States
    A Versatile Isobaric Tag Enables Proteome Quantification in Data Dependent and Data Independent Acquisition Mode, Xiaobo Tian, The Netherlands
    Ion Mobility Separation in a TIMS-TOF PASEF Acquisition Method Decreases Spectral Complexity, Joshua Charkow, Canada
    Protein Context Shapes the Specificity of Domain-Peptide Interactions in Vivo, Ugo Dionne, Canada
    Spatially Resolved Proteome Profiling of FFPE Tissues, Andikan Nwosu, United States
    Dissecting the Ontogenic Remodeling of the Proteomic Landscape and Functionality of Hematopoietic Progenitor Cells in Normal Development and Leukemia, Maria Jassinskaja, Sweden
    Identification of Autoantigens with Diagnostic Ability of Colorectal Cancer by Immunoprecipitation Coupled to Mass Spectrometry, Ana Montero Calle, Spain
    Preservation of Trypsin Activity at Elevated Temperatures for Optimized Proteome Digestion, Jessica Nickerson, Canada

  • The Synergies of Mass Spectrometry and Informatics, John R. Yates
    New prm-PASEF® Method for Highly Multiplexed Targeted Quantitative Proteomics for Clinical Research, Gunnar Dittmar

    This industry seminar is supported by:
    For more details on the virtual Industry Seminars, please visit the Confirmed Sponsors & Virtual Seminars page.

  • Chair: Rob Mortiz, United States
    Co-Chair: Maggie Lam, United States
    ATLANTiC: Proteome Activity Landscapes of Tumor Cell Lines Determine Drug Responses, Bernhard Kuster, Germany
    Deep Visual Proteomics for Systems Biology, Matthias Mann, Germany
    Regulation of Hypoxia-inducible Factors by Oxygen-dependent Degradation, Gregg Semenza, United States

    This session is supported by:

  • Chair: Susan Weintraub, United States
    Co-Chair: Justyna Fert-Bober, United States
    Development of a Pan-coronavirus Proteome Serological Assay, Josh LaBaer, United States
    The 3D Proteome and the Potential for Conformational Biomarkers, John Yates, United States
    Protein Biomarker Quantification by LCMS Enabling Gene Therapy and Biotherapeutics Development in Biopharma, Hendrik Neubert, United States

    This session is supported by:

  • Chair: Fernando Corrales, Spain
    Co-Chair: Michael Roehrl, United States
    In-cell Protein Footprinting: A Tool for Structural Biology Across the Proteome, Lisa Jones, United States
    Single-cell Proteomic and Transcriptomic Analysis of Macrophage Heterogeneity, Nikolai Slovov, United States
    Mass Spectrometry Proteomics for Single-cell Neuroscience, Peter Nemes, United States

    This session is supported by:

  • Chair: Mathieu Lavallée-Adam, Canada
    Career, Family and Work-Life, Balance, Benjamin A. Garcia, United States
    Work-Life Balance Especially During the COVID-19 Pandemic, Ruth Huttenhain, United States

  • Live Annual General Meeting and Kahoot Quiz

  • Chairs: Maike Langini, Germany, Andreas Hober, Sweden
    The Industry Needs You, Bernard Delanghe, United States
    Publishing: A Career Beyond Academia, James Anson, United Kingdom

  • Chair: Peter Hoffman, Australia
    Co-Chair: Maike Langini, United Kingdom
    Rapid Complex-centric Quantitative Profiling of the Monocyte-macrophage Axis, Ben Collins, United Kingdom
    Proteomes in 3D, Paola Picotti, Switzerland
    Cellular Cartography Using Crosslinking Mass Spectrometry, Juri Rappsilber, United Kingdom

  • Chair: Andrea Urbani, Italy
    Co-Chair: Chia-Li Han, Taiwan
    Computational Discovery of Tumor Antigens from Mass Spectrometry Data, Bing Zhang, United States
    Exploring the Landscape of Pan-cancer Proteogenomics with Cancer Cell Lines, Rebecca Poulos, Australia
    Genetics of Protein Abundance in Human TIssues, Hua Tang, United States

  • Chair: Ileana Cristea, United States
    Co-Chair: James Waddington, Ireland
    Defining Proteoform Landscape by Novel Top-down Proteomics Strategies, Ying Ge, United States
    Building an Ecosystem to Measure and Understand Human Biology at the Proteoform Level, Neil Kelleher, United States
    Challenges to Unveil Human Proteoform Landscape by Shotgun Proteomics Approaches, Yasushi Ishihama, Japan

  • Chairs: Maike Langini, Ruth Huttenhain
    Mechanism of adrenergic CaV1.2 stimulation revealed by proximity proteomics, Marian Kalocsay, United States
    Sleep-wake cycles drive daily dynamics of synaptic phosphorylation, Maria Robles, Germany
    The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest, Jakob Trendel, Germany

  • Multi-omic analysis of two common p53 mutations: Proteins regulated by mutated p53 as potential targets for immunotherapy, Christie Hunter, David Boocock
    This industry seminar is supported by:
    For more details on the virtual Industry Seminars, please visit the Confirmed Sponsors & Virtual Seminars page.

  • Multiplexed Proteomics for Understanding Molecular Biology, Mikhail Savitski, Denmark
    Characterizing Cellular Hierarchies Using Quantitative Single-Cell Proteomics, Erwin Schoof, Germany

    This industry seminar is supported by:
    For more details on the virtual Industry Seminars, please visit the Confirmed Sponsors & Virtual Seminars page.

  • Chair: Gyorgy Marko-Varga, Sweden
    Co-Chair: Svetlana Murzina, Russia
    Rapid Complex-centric Quantitative Profiling of the Monocyte-macrophage Axis, Ben Collins, United Kingdom
    Proteomes in 3D, Paola Picotti, Switzerland
    Cellular Cartography Using Crosslinking Mass Spectrometry, Juri Rappsilber, United Kingdom

  • Chair:Henry Rodriguez, United States
    Co-Chair: Tim Van Den Bossche, Belgium
    Computational Discovery of Tumor Antigens from Mass Spectrometry Data, Bing Zhang, United States
    Exploring the Landscape of Pan-cancer Proteogenomics with Cancer Cell Lines, Rebecca Poulos, Australia
    Genetics of Protein Abundance in Human TIssues, Hua Tang, United States

  • Chair: Frank Schmidt, Qatar
    Co-Chair: Ruth Huttenhain, United States
    Defining Proteoform Landscape by Novel Top-down Proteomics Strategies, Ying Ge, United States
    Building an Ecosystem to Measure and Understand Human Biology at the Proteoform Level, Neil Kelleher, United States
    Challenges to Unveil Human Proteoform Landscape by Shotgun Proteomics Approaches, Yasushi Ishihama, Japan

  • Closing Remarks
    Announcement of the PhD Poster and ECR Manuscript Winners
    HUPO Awards
    Ben Collins, Ireland
    Benjamin A. Garcia, United States
    Fuchu He, China
    Karin Rodland, United States
    Melvin Park, United States
    Oliver Raether, United States
    Tadashi Yamamoto, Japan
    Announcement of HUPO 2021 Programme

  • Chairs: Robert Moritz, United States, Sue Weintraub, United States
    Relevance and Future Projections of Proteomics in the Pharmaceutical Industry, Jennie Lil, United States
    Translating Proteomics to the Clinical Arena, Michael Roehrl, United States
    Target 2035 - Pharmacological Modulators for All Human Proteins, Cheryl Arrowsmith, Canada
    Expanding Proteomics Beyond the Proteomic Community, Jochen Schwenk, Sweden
    Bringing context to substance, Relevance of the Human Proteome Project, Robert Moritz, United States
    Review and Updates (Future Planning/Developments)
    - C-HPP, Chris Overall, United States
    - B/D-HPP, Ileana Cristea, United States
    - Initiatives and 4 Resource Pillars, Cecilia Lindskog, Sweden, Eric Deutsch, United States, Lydie Lane, Switzerland, Ed Nice, Australia, Michael Roehrl, United States and Susan Weintraub, United States
    Written Questions from the Floor

  • Chairs: Ruedi Aebersold, Switzerland, Rebekah Gundry, United States
    Background and Outline, Ruedi Aebersold, Switzerland
    SAB Session with 3 Break-Out Groups, All
    - Breakout I. How can proteomics make the link from measuring molecules (proteins) to biological function?
    Rapporteur:Juri Rappsilber, Germany
    - Breakout II. HPP can claim that the discovery of exemplary proteins from almost all human loci can be confidently detected and routinely measured. How does HPP build on that to advance life science and clinical research? In other words, how can we explore ( e.g. within HPP) the full extent of the complexities of the proteome and how can this be translated into new biology?
    Rapporteur: Kathryn Lilley, UK
    - Breakout III. What are the bottlenecks to increase the uptake and dissemination of proteomics?
    Rapporteur: Cathy Costello, United States
    Summary Reports to Combined Group, All

  • Chairs: Cecilia Lindskog, Sweden, Ed Nice, Australia
    Human Cell Atlas/Chan Zuckerberg Foundation/International Opportunities, Emma Lundberg, Sweden, Neil Kelleher, United States
    International HUPO External Development Initiative Panel, Sudhir Srivastava, United States, Sanjeeva Srivastava, India,
    Kristin E Burnum-Johnson, United States, Eleftherios Diamandis, Canada, Anthony Whetton, United Kingdom
    USA and Cancer Moonshot Opportunities, Mike Snyder, United States, Henry Rodriguez, United States
    Other Opportunities from the Floor
    Incoming HUPO Presidential Address to the HPP, Yu-Ju Chen, Taiwan

For more details on the virtual Industry Seminars, please visit the Confirmed Sponsors & Virtual Seminars page.